Spinecare Topics
Advancements in Spine Care and Spine Surgery
Use of Biomaterials for Spinal Implants
Spine implants are used to facilitate fusion, correct deformities, stabilize and strengthen the spine. Conditions that often require surgical placement of implants/instrumentation include instability (to much movement) of a spinal segment such as that seen with spondylolisthesis, chronic degenerative disc disease, traumatic fracture, and other forms of spinal instability including scoliosis. The types of spinal implants can be summarized as follows: rods, pedicle screws, hooks, plates and cages. Most spinal implants are made of metals such as titanium, titanium-alloy or non ferrous materials; some are made of non-metallic compounds that do not “blur CT and MRI images like stainless steel. Non-metallic compounds of biomaterials are emerging as a favorable alternative.
Bone Morphogenetic Proteins (BMP)
Advances in molecular biology continue to contribute to the field of spine surgery, particularly in the areas of tissue remodeling, spinal fusion and with the use of spinal implants. Genetically engineered proteins referred to as Bone Morphological Proteins have become available for use during spine surgery to help create bone fusion. Bone morphogenetic proteins (BMPs) regulate bone healing. When added to biomaterials, BMPs change the way the body reacts to the materials. The combination of BMPs and specialized biomaterials forms an effective bone graft substitute. BMPs speed up bone healing and appear to help reduce the risk for host rejection of bone graft.
BMPs can be placed into biomaterials such as a collagen-like sponge, within ceramic implants and a variety of polymers when bone fusion is desirable. These biomaterials act as a conduit for BMP, and serve to provide support and tissue spacing when necessary. In the near future BMPs may be placed into biodegradable material that will be used as an intra-operative spacer of tissue and to facilitate spinal fusion. The use of the BMPs will likely replace the need for autologous or allograft bone grafts.
Bone morphogenic proteins (BMP) are substances that stimulate bone growth and can be based on and matched to properly identified material from the patient. Material such as BMP can be used to produce a spinal fusion without the additional pain of using the patient's own bone for this purpose. BMP can be implanted to allow support for the structure of the spine in a way that bone grafts have difficulty doing. BMP relies on the patient's own genetic makeup to provide safe, effective bone growth for the patient.
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